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In-Body Gene Editing Is Here and It Could Drastically Change How We Treat Disease

Brian Madeux recently became the first individual ever to receive in-body gene editing, in an attempt to treat Hunter Syndrome, a rare metabolic condition tied to a genetic mutation.

Brian Madeux. (Screenshot via Youtube)

Our DNA has the power to unlock endless stories of who we are and where we came from, but what if we could change it forever? 44-year old Brian Madeux may be among the first to know: Last month, Madeux was the first individual to receive in-body gene editing, in an attempt to treat his Hunter Syndrome, a rare metabolic condition tied to a genetic mutation.

To carry out this groundbreaking therapy, scientists flooded Madeux’s body via IV with billions of copies of a corrective gene, as well as with a gene editor known as zinc finger nuclease (ZFN), intended to insert the new gene into his DNA.

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