Leonard Nimoy, the iconic and beloved actor who gained a worldwide following for his portrayal of the ever-logical and resolute Mr. Spock on Star Trek, passed away on Friday in his home in Los Angeles. Nimoy was 83.

He is survived by his wife, Susan Bay Nimoy, who confirmed his death was caused by end-stage chronic obstructive pulmonary disease. Nimoy had been fighting this disease after years of smoking, despite having given up the habit three decades ago.

Condolences have begun to pour in from around the world, as a saddened fanbase recalled, somewhat ironically, the humanity that Nimoy brought to the half-Vulcan he played. Besides acting, Nimoy’s pursuits included photography, poetry and music, but he will always be remembered for the iconic character of Mr. Spock, a pointy-eared Second Officer with an unmistakable hand signal, a formidable Vulcan nerve pinch, and even his own catch phrase: “Live long and prosper”—a motto Nimoy himself embodied.